This video discusses the root cause of fatigue, brain fog, and inflammation as chronic inflammation and its impact on brain function, energy levels, and thyroid health. Dr. Anshul Gupta introduces three science-backed nutrients—magnesium, omega-3 fatty acids (EPA & DHA), and vitamin D3 with K2—to combat these issues, detailing their benefits and optimal dosages.
Magnesium: Crucial for over 300 biochemical reactions, magnesium deficiency is a potential undiagnosed cause of fatigue, brain fog, and inflammation. It reduces inflammation by controlling the NF-κappa B gene, aids mitochondrial energy production, and assists in thyroid hormone conversion (T4 to T3). Magnesium glycinate is recommended, especially before bed.
Omega-3 Fatty Acids (EPA & DHA): Essential for brain health and inflammation reduction. A minimum of 1000-2000 mg of EPA and DHA is needed daily for optimal benefits. While fish provides omega-3s, consistent consumption of fatty fish (3-4 times/week) is necessary, and concerns about mercury levels exist.
Vitamin D3 + K2: Important for brain cell protection against inflammation, neurotransmitter production, and overall inflammation control. Vitamin D3 requires K2 for proper absorption and deposition; adequate magnesium is also needed for its metabolism. Higher dosages (2000-5000 IU) are often necessary, and combining it with K2 and a fatty meal enhances absorption. The speaker notes that vitamin D may be better described as a hormone than a vitamin.