About this video

• Video Title: 5 Supplements To Slow Aging (Scientist Explains)
• Channel: Tim Ferriss
• Speakers: Tim Ferriss, Scientist (unnamed)
• Duration: 00:05:06

Overview

This video discusses five key supplements that may help slow aging, with a scientist explaining their benefits and potential considerations. The conversation covers CoQ10 (and its more absorbable form, ibanone), creatine, Vitamin D, melatonin, and omega-3 fatty acids.

Key takeaways

• CoQ10/Ibanone: Recommended for cardiovascular health, especially for those on statins or metformin which can deplete CoQ10. While the speaker doesn't personally take it due to dietary intake, they note its benefits. Ibanone is a stabilized form, once part of the Deanna protocol for ALS. Ubiquininal is suggested as a substitute. High doses in animal models showed potential kidney toxicity, but this may not apply to commercially available forms.
• Creatine Monohydrate: A long-standing supplement for the speaker, it is also discussed for potential benefits in Alzheimer's disease. High doses (10-20 grams) are mentioned for severe cases, with a caution for split dosing. It's also noted for aiding recovery from sleep deprivation.
• Vitamin D: Essential to supplement, but levels should be monitored via lab tests. Ideal levels are suggested to be between 60-80, avoiding levels over 100. Even with sun exposure, supplementation may be necessary.
• Melatonin: Recommended as a neuroprotective antioxidant supplement to be taken at nighttime.
• Omega-3 Fatty Acids (EPA/DHA): The speaker personally doesn't supplement due to high levels from diet (fish consumption). OmegaQuant testing can assess levels. If not consuming enough fish, Nordic Naturals is suggested as a reliable brand. It's anticipated that EPA/DHA levels will become a standard part of blood work in the future.

The transcript mentions that "idenone is sort of more absorbable version of CoQ10" and later states, "But I think ubiquininal or CoQ10, it would be a good substitute for that [Ibanone]." The speaker also notes that Ibanone became a drug and was no longer available on Amazon. While the transcript does distinguish between them and suggests ubiquininal as a substitute, it initially frames ibanone as a more absorbable version of CoQ10.