BPC-157: Everything You Need to Know—Benefits, Risks, Dosing, & Delivery Methods

About this video

• Video Title: BPC-157: Everything You Need to Know—Benefits, Risks, Dosing, & Delivery Methods
• Channel: Quinn Stillson MD
• Speakers: Quinn Stillson MD
• Duration: 00:32:35

Overview

This video provides a comprehensive overview of BPC-157, a peptide derived from human gastric juice. It explores its mechanisms of action, potential benefits for musculoskeletal, gut, brain, and heart health, as well as its risks, particularly concerning cancer. The video also discusses various delivery methods, optimal dosing, timing, cycle length, and how to source BPC-157, emphasizing the importance of third-party testing.

Key takeaways

• Mechanism of Action: BPC-157 works by increasing nitric oxide synthesis, promoting vasodilation and inhibiting platelet aggregation, and upregulating vascular endothelial growth factor (VEGF) for angiogenesis, thereby improving blood flow and directly aiding tissue repair through collagen synthesis and increased growth hormone receptors on fibroblasts.
• Potential Benefits: The peptide shows promise in healing musculoskeletal injuries (tendons, ligaments, muscles, bones), improving gut health (IBD, anastomotic healing, NSAID-induced ulcers), enhancing brain and nerve health (stroke recovery, TBI, nerve repair, mood regulation), and potentially benefiting cardiovascular health.
• Risks and Safety Concerns: A significant concern is the lack of robust human safety data. Theoretically, BPC-157's angiogenic properties could promote cancer growth and spread. Other potential risks include unknown short-term side effects due to limited human trials and theoretical impacts on immune surveillance.
• Delivery Methods and Dosing: Subcutaneous injection is generally considered the most effective for systemic absorption, followed by oral administration. Oral forms are preferred for gut health. Dosing is speculative, with theoretical calculations from animal studies and anecdotal human reports suggesting ranges for both injectable and oral forms.
• Sourcing and Usage Recommendations: Due to its unapproved status, sourcing BPC-157 requires caution. High-quality suppliers should provide third-party testing for purity, identification, endotoxin levels, and sterility. The recommendation is for short-term, targeted use (4-8 weeks) for specific injuries or gut issues, after thorough cancer screening, and not for continuous or preventative use.