This video introduces the concepts of linear combinations, span, and basis vectors in the context of linear algebra. It explains how coordinates can be interpreted as scalars that scale basis vectors, and how the sum of these scaled vectors forms a linear combination. The video further explores the geometric interpretation of the span of vectors as the set of all reachable vectors through linear combinations, illustrating this in 2D and 3D space. Finally, it defines linear dependence and independence and introduces the technical definition of a basis.