MK-677: Muscle Growth & Anti-Aging

About this video

• Video Title: MK-677: Muscle Growth & Anti-Aging
• Channel: Peptide Insights
• Speakers: (Speaker names not explicitly mentioned in the transcript)
• Duration: 00:14:13

Overview

This video provides a comprehensive overview of MK-677, an oral compound that stimulates growth hormone release. It explains how MK-677 works, its benefits for muscle growth and anti-aging, potential side effects and contraindications, recommended dosages and cycling, and how it compares to SARMs and peptides. The video also discusses stacking MK-677 with other peptides and supplements, lifestyle adjustments to optimize its effects, and the speaker's personal opinion on its use.

Key takeaways

• Mechanism of Action: MK-677 is a non-peptide ghrelin agonist that works by stimulating ghrelin receptors in the pituitary gland, leading to increased release of growth hormone and IGF-1.
• Benefits: Increased lean muscle mass, fat reduction, enhanced recovery (muscle, ligaments, joints), improved sleep quality, better skin health, and protective effects on the brain and heart.
• Distinction from Peptides and SARMs: Unlike peptides, MK-677 is oral and has a longer half-life. Unlike SARMs, it does not suppress hormones and lacks androgenic/anabolic effects related to testosterone.
• Cautions and Contraindications: Potential side effects include increased hunger, water retention, elevated blood sugar, and increased prolactin. It is contraindicated for pregnant individuals, those with a history of hormone-sensitive cancers, and uncontrolled diabetes.
• Dosage and Cycling: Recommended dosage is 5-25 mg daily, with females often using half that dose. Cycling typically involves 4-8 weeks on and 4-8 weeks off, with a strong caution against prolonged high-dose use due to potential health risks.
• Stacking and Lifestyle: Can be stacked with recovery peptides and certain supplements like natural diuretics and collagen. Lifestyle tools like fasting, semen retention, sun exposure, sleep, corrective training, and specific diets can complement its use.
• Speaker's Opinion: While initially hesitant due to its potency and potential for abuse, the speaker now finds MK-677 a viable option with proper research, sourcing, and conservative dosing, though they would prefer an oral peptide like Sorlin for a gentler approach.