This video features a conversation between Steven Bartlett and Dr. Lisa Mosconi, a neuroscientist specializing in women's brain health and menopause. The main focus is on the often-overlooked neurological impacts of menopause, dispelling myths and presenting new research on brain changes during this life stage. The discussion also covers lifestyle adjustments to mitigate symptoms and improve overall well-being during and after menopause.
Menopause significantly impacts the brain: Menopause causes measurable changes in brain structure, function, and energy levels (a 30% drop in brain energy was shown via brain scans). This explains many commonly reported symptoms like brain fog, memory loss, and mood changes. These are neurological symptoms, not solely hormonal.
Menopause is a process, not an event: The transition to menopause is a multi-year process involving various stages (premenopause, perimenopause, menopause, and postmenopause), each with unique symptoms. The perimenopausal transition can last 7-14 years.
Lifestyle adjustments are crucial: Diet, exercise, sleep hygiene, stress management, and toxin avoidance are essential for mitigating menopause symptoms and improving brain health. A Mediterranean-style diet rich in antioxidants and omega-3s is recommended. Regular exercise, particularly moderate-intensity cardiovascular activity, is beneficial.
Hormone Replacement Therapy (HRT) has a complex history: While HRT can be effective, it requires careful consideration due to past controversies and potential risks. Modern approaches utilize lower doses, bioidentical hormones, and targeted delivery methods. Using HRT during perimenopause to stabilize hormones can be more beneficial than using it after menopause.
Research is ongoing: Dr. Mosconi highlights the need for more research, especially on the impact of menopause on different racial/ethnic groups and the use of HRT during the perimenopausal transition. She mentions a clinical trial underway testing a "designer estrogen" that targets brain health without impacting breast tissue.