The Most Potent Longevity Hormone you’ve Never Heard - and How to Activate it, Naturally

About this Video

• Video Title: The Most Potent Longevity Hormone you’ve Never Heard - and How to Activate it, Naturally
• Channel: Physionic
• Speakers: [The speaker's name is not provided in the transcript.]
• Duration: 15:02

Introduction

This video explores FGF-21, a hormone linked to longevity. The speaker presents scientific evidence from mouse studies and human studies demonstrating FGF-21's positive effects on lifespan, body composition, and insulin sensitivity. The video also explains how to naturally increase FGF-21 levels.

Key Takeaways

• FGF-21 and Longevity: Studies in mice show that increased FGF-21 levels significantly extend lifespan (approximately 26%), improve body composition (reduced body fat, increased lean mass), and enhance metabolic rate. These mice also showed improved liver health and reduced insulin resistance.
• FGF-21 Mechanisms: FGF-21's benefits are linked to its effect on fat cells, reducing fat release and lowering ceramide levels, which improves insulin sensitivity and protects organs from ectopic fat accumulation.
• Increasing FGF-21 in Humans: A human study suggests that reducing protein intake to 9% of total daily calories can increase FGF-21 levels, thereby improving insulin sensitivity.
• Cautions: The human study had limitations (young, healthy men, no exercise), and the optimal protein reduction strategy may vary based on age and activity level. Further research is needed, particularly on older populations.
• Additional Information: The speaker mentions that a more detailed exploration of FGF-21’s effects (immune system, interaction with other hormones, etc.) is available in the extended version of the video for Physionic Insiders.