This video discusses studies on aged garlic extract (AGE) as a natural supplement that may reduce plaque buildup in arteries. The video presents findings from various trials, highlighting both the promising results and the limitations of current research.
Aged Garlic Extract and Calcium Accumulation: Studies show AGE supplementation can slow down calcium accumulation in arteries. One study showed a significant difference (three times less calcium increase) in the AGE group compared to a placebo group.
Total Plaque Volume Reduction: Another study found that 900 mg of garlic powder daily prevented plaque growth and even led to a slight reduction (2-3%) in total plaque volume, particularly in women.
Impact on Low Attenuation Plaque: More recent research using computed tomography angiography (CTA) focused on low-attenuation plaque (necrotic core), a marker of high-risk plaque. Studies showed AGE supplementation significantly reduced this type of plaque in diabetic and metabolic syndrome patients. One trial showed a 29% decrease in low-attenuation plaque with a 2.4g daily dose of AGE, compared to a 57% increase in the control group.
Limitations of Existing Research: The video acknowledges limitations in the existing research, including relatively small sample sizes, focus on surrogate markers (plaque measurements), and lack of large-scale studies on the actual risk reduction of heart attacks and strokes.
