Top 4 Most Underrated Glutathione Boosters

About this video

• Video Title: Top 4 Most Underrated Glutathione Boosters
• Channel: Felix Harder
• Speakers: Felix Harder
• Duration: 00:09:16

Overview

This video discusses four underrated nutrients that can significantly boost glutathione levels and improve its utilization and recycling in the body. The speaker emphasizes that standard glutathione supplements may not be effective if these underlying nutrients are deficient, leading to wasted money and missed benefits.

Key takeaways

• Selenium is crucial for glutathione peroxidase: This enzyme neutralizes harmful reactive molecules like hydrogen peroxide, and its function is dependent on selenium. A deficiency can render the enzyme ineffective, leading to increased oxidative stress. Brazil nuts are an excellent source, and supplements like selenium yeast or selenomethionine are bioavailable.
• Molybdenum supports detoxification pathways: It is essential for converting toxic sulfite (a byproduct of glutathione detoxifying sulfur-based compounds) into harmless sulfate, and also helps break down acetaldehyde. While outright deficiency is rare, functional deficiency can occur, especially in individuals sensitive to sulfur.
• Sulforaphane activates the NRF2 pathway: Found in cruciferous vegetables like broccoli sprouts, sulforaphane boosts the production of glutathione by upregulating enzymes like glutamate cysteine ligase (GCL), the rate-limiting step in glutathione synthesis. It also increases glutathione reductase, which recycles used glutathione.
• Melatonin acts as a potent antioxidant and glutathione booster: Beyond its role in sleep regulation, melatonin directly stimulates glutathione production by increasing the activity of GCL and glutathione reductase. It also scavenges free radicals, reducing oxidative burden and sparing glutathione. Natural sources include reducing blue light exposure, sleeping in darkness, and morning sunlight, but low-dose supplements can also be effective.