This video recounts the history of the Whitman Mission in the Walla Walla Valley, focusing on the arrival of Marcus and Narcissa Whitman, the first non-Native American women to cross the continent, and their missionary work among the Cayuse people. It details the escalating tensions, cultural misunderstandings, disease outbreaks, and the eventual massacre at the mission in 1847, highlighting the tragic consequences of cultural clash and the lasting impact on the Cayuse people and the westward expansion of the United States.