This video demonstrates a method to disable Windows Defender by tricking the system into believing a third-party antivirus is installed. The creator uses a GitHub project called "No Defender" to replace Windows Defender with a Donkey Kong theme, highlighting the vulnerability and ease with which Windows Defender can be bypassed. The video also touches upon the security implications and briefly introduces Threat Locker as a more robust security solution using a zero-trust, default-deny approach.